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The PlayStation Portable ( PSP ) is a handheld game console developed by Sony .  Development of the console was announced during E3 2003 ,  and it was unveiled on May 11 , 2004, at a Sony press conference before E3 2004.  The system was released in Japan on December 12 , 2004,  in North America on March 24 , 2005,  and in the PAL region on September 1 , 2005.  It primarily competed with the Nintendo DS , as part of the seventh generation of video games.
Progressive supranuclear palsy ( PSP ; or the Steele-Richardson-Olszewski syndrome , after the doctors who described it in 1963) is a degenerative disease involving the gradual deterioration and death of specific volumes of the brain .   Males and females are affected approximately equally and there is no racial, geographical or occupational predilection. Approximately 6 people per 100,000 population have PSP. It has been described as a tauopathy .